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katy Guest
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Posted: Thu Oct 02, 2008 9:42 pm Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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I was just diagnosed with celiac disease at the age of 56 after a bad
case of shingles. After a endoscopy>s, endoscopy and blood work for
every parasitical condition in the world, they did the celiac blood test
and then cross referenced to the results of the endoscopy and
colonoscopy. Said the results were at the high end of the table and that
the celiac disease caused microscopic colitis. I took the herpes
medication but it had no effect on the shingles, diarrhea, or anything
else that I could tell. Neither my gastroenterologist or the internist
made any correlation between the celiac disease and the shingles, so I
am going to bring that to their attention. Turns out that over the years
I have been misdiagnosed with various other food allergies and
conditions when all along I had celiac disease. At least now I know. |
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Robert Miles Guest
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Posted: Fri Oct 03, 2008 12:42 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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"Kofi" <kofi@anon.un> wrote in message
news:kofi-5B3ECA.00092502102008@news.west.earthlink.net...
[quote]In article
b4d6b68f-f426-48d1-b345-436dd1fe44e7@l42g2000hsc.googlegroups.com>,
jackson.alonso@googlemail.com wrote:
Kofi, what are your palns to treat the infection? It is well known
that herpesviri modulate the immune system towards a Th2 shift by
producing the necessary ILs. However we still lack efficient methods
of diagnosis as well as treatment
Well, my IgG/IgM titers seem to be pretty accurate. Varicella and CMV
fit a good number of symptoms. What bothers me are those chronic
infections I might have that aren>t prompting an antibody response. I
suppose those require PCR. What we really need are shotgun chips that
look for thousands of antibodies and fragments of pathogen DNA/RNA at
once. With modern chip fabrication techniques, economies of scale could
churn them out pretty cheaply. Sadly, I>m not aware of any push in
microfluidics to put something like this on the market any time soon.
Having said that, I>ve got a definite viral problem. I>ve suspected
something like this for a long time, but with a condition this
complicated, I>ve had little other choice than peeling each layer of the
onion one at a time. The viruses are simply the most recent layer
that>s stuck to the onion. I>ve done well on the chlorella and this
seems to indicate I didn>t fully take care of the earliest, most obvious
layer - the mercury poisoning. There>s not much recent in the pubmed
literature, but there are some intriguing abstracts on mercury, CMV and
chlorella (in fact, I>m surprised the NIH slipped up and let them
through). There seems to be a viscious cycle involving local mercury
deposits left over in my gut after detox (apparently the DMPS missed
them; low blood flow, maybe?), resistance to growth hormone in those
areas and viral infection [PMID 8931761, 8686573, 7526487, 8686573].
[snip][/quote]
You may want to run a program in the background on your computer to
help virus research.
This one helps herpes research, but doesn>t emphasize it; also HIV:
http://boinc.bakerlab.org/rosetta/
World Community Grid - dengue and HIV; also the proteosome
project helps somewhat
http://www.worldcommunitygrid.org/index.jsp
You mentioned also being interested in cell adhesion. This one is
developing software to help research into that:
http://cels-at-home-dev.dyndns.org/cels/
You might want to participate in all of these on the same
computer to fill in times when one or more of them doesn>t
have any workunits they need you to work on; I participate in
all of these projects and more with my computer.
Those interested in allergies or autoimmune conditions may want to
participate in some of protein folding projects. I also participate in
these:
World Community Grid - proteome
http://www.worldcommunitygrid.org/
POEM@HOME
http://boinc.fzk.de/poem/
boincsimap
http://boinc.bio.wzw.tum.de/boincsimap/
There are even much projects still in alpha test or beta test, but
I don>t consider those suitable for the general public to
participate yet.
Also, there>s a web site for herpes sufferers. Seems to have
problems with registering new members, though.
<http://www.righthealth.com/Health/Herpes%20C-s?lid=goog-ads-sb-8536643334>
These sites may be relevant to your herpes problem:
http://jn.nutrition.org/cgi/content/full/138/1/130
http://www.pnas.org/content/97/5/2208.full
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1559766
http://books.nap.edu/openbook.php?record_id=6450&page=249
http://www.immunesupport.com/chronic-fatigue-syndrome-causes.htm
I found them with a Google search for "herpes IL-10 vitamin C"
without the quotes. |
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Kofi Guest
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Posted: Fri Oct 03, 2008 1:18 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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[quote]The best site on HHV6 definitely is http://www.hhv-6foundation.org/.
They have all the latest info on it, as well as the best scientists in
this field.
[/quote]
Thanks. Did you know HHV6 integrates into the genome? I>ve found that
and some other stuff on sciencedaily.com. I>ll try to post it soon.
[quote]It>s scary that they are allowed the title immunologist while
actually they know so little and act the opposite. Their knowledge is
based on what they learned in university and that>s it. This is just a
waste of brain. Develop a DVD that lists all symptoms, let the user
type in the symptoms. Now bring up the tests the user is supposed to
do. Make those tests. Type in the test results and bring up the most
probable illness. Show the treatment. Done. You don>t need very
intelligent people for that. You need the most intelligent people
however to connect the dots on pubmed and develop that DVD and the
tests and the treatment. To connect symptom to test and treatment
could nearly be done by anyone.
[/quote]
Well, if I got to go to Congress and pass laws that protected plumbers
from being sued if they ever left a job half-finished, everybody would
take plumbing classes and do their own plumbing wherever possible. What
you see in the medical industry is a lack of scientific efficiency.
These guys refused to listen to statistical quality control. They
totally ignored Edwards Deming. Detroit ignored him in the '50s and
'60s but Japan didn>t and the Japanese car companies nearly bankrupted
Detroit in the '80s. Today>s problems in Detroit stem from the fact
that the car companies have been successful for the last twenty years in
bribing Congress to protect them from rising CAFE (fuel efficiency)
standards. It>s rent-seeking - the use of political connections to
protect an industry from the discipline of market forces. I studied
that in graduate school along with microeconomics, which is how I know
exactly what cognitive mistakes doctors make and why they make them.
The medical business is protected from being held responsible for its
decisions. I don>t think we>re ever going to have enough international
competition in medical care to fully address it - not the way we did
with imported cars, anyway.
So if you pay a plumber if he does a bad job and you pay him if he does
a good job, what kind of a job is he more likely to do? It doesn>t take
a genius to figure that out. What it does take is someone trained to
see market reality and not somebody trained in any sort of ideology that
fits reality into neat little boxes before you can examine it for
yourself. But economists aren>t usually trained to see reality like
this either. I have expertise in literary theory and political science
to thank for that. A liberal arts education and a sense of history are
invaluable in any undertaking. They really give you a deep capacity for
independent thought.
If we gave patients strong property rights and the ability to audit
their health care with outside experts, patients wouldn>t have to deal
with the equivalent of sub-prime CDO meltdowns every day. The
government didn>t audit the credit quality of the mortgages going into
CDOs and now global credit markets are melting down. This happened
because of a "free market" deregulatory atmosphere in the Republican
party. Republicans have been fighting with the New Deal state since its
inception in the 1930s. Bush has in fact behaved like a Communist, not
a capitalist. It>s the job of the government to enforce property
rights. Murder, for instance, is a regulation. If you stopped
enforcing the laws against murder, you>d have more murders. Bush
stopped enforcing the laws against fraud because he believed businessmen
never commit sins and government always does. The result is massive
amounts of fraud. But this was foreseeable. His family has always done
this in office.
Passing laws restricting the ability to sue for medical malpractice
results in more malpractice, plain and simple. You>re taking away a
patient>s most fundamental property right - his ownership of himself.
If a doctor can injure somebody and still get paid the same amount, how
much more likely is it you>ll see injuries? The data shows exactly
this. In states where it>s easier to sue, the quality of medical care
is higher. Lawyering is easy. I can find one lawyer who will sue the
shit out of another lawyer for malpractice. From what I>ve seen, legal
malpractice is rarer but it does happen and it gets dealt with. How
many doctors will sue another doctor or testify against one? The
doctors I>ve seen doing the right thing locally almost always get
punished for it even in the most egregious cases of malpractice -
because a scientific standard of care is not what the courts deal with
(if for no other reason than our understand of the law is much less
opaque than our understanding of the human body).
What you>re suggesting is a Google-like search system matching symptoms
with likely diagnoses and then evaluating the cost-effectiveness of
various approaches. That>s great. I>m all for it. It>s got its
problems, but it>s infinitely better than the current system in America.
The problem is, seven years ago when I got sick I realized you could
never have that approach as long as various parts of the puzzle have
political protection from market responsibility. People are getting
paid *not* to do things that way and they will lose money if you change.
You can>t even collect the data to make such a system work in America.
For instance, is it really in a drug company>s interest if a database
keeps a record of people who benefit or don>t benefit from their drugs?
Merck has an incentive to sell as many different drugs to as many
different people as possible. It>s only due to government regulations
that the market is protected from this - at least it>s supposed to be.
If the government were really doing its jobs do you think we>d have so
many ads for prescription drugs on TV? How many people watching "Chuck"
are smart enough to write their own medical prescriptions? How many
people, for that matter, are smart enough to do their own health care
audits? The industry is rife with information asymmetry, as we say in
game theory. There are ways around agent loss problems but the people
giving money to congressional campaigns have been deliberately picking
candidates who are dumb and easily manipulated - moreso than in past
years. It>s all about raising money to buy TV ads now. Congress spends
a fraction of the time in committee studying problems that it used to.
People don>t fix these issues. *Institutions* do.
The government won>t stop Celebrex from getting peddled to toddlers on
TV even though we have known for years than blocking COX-2 makes
autoimmune conditions worse. If the government can>t protect
information quality on TV, what do you think they can do when drug reps
talk to doctors in a private office where there>s much less of a
spotlight on the relationship?
Don>t get me wrong. You have to keep your eye on government too, but
what you>re seeing right now is what happens when special
interests/rent-seekers have protected themselves for a generation from
political responsibility - whether it>s credit card companies charging
100% interest a year now or medical providers totally ignoring quality
of service. The result is inefficiency that drags down economic growth.
By the way, if you think I>m smart now, you should have seen me twenty
years ago. I could do this stuff and juggle a dozen other balls at the
same time. Seven years ago, I was so sick I couldn>t hold a
conversation and it took me about an hour to read and understand a
paragraph. To say I was in severe pain would be like saying Saddam
Hussein inconvenienced his political opponents. I had to take detailed
notes from everything I read and compare them in lists. It was the only
way I could remember anything. I kept doing that until it stuck. If I
wanted to talk, I would type up sentences in my mind>s eye and read them
back. It was awkward, but it worked until I could patch the major holes
in my hull and start the pumps. I was taught to be flexible from an
early age, even under great pain. What can I say? Some lessons you can
only learn in athletics - which we, as a society, have priced out of the
reach of the ordinary person which is why we>re now getting fat on
school cafeteria pizzas.
There is a cost to society when you butcher your best and brightest this
way. Getting that through to even John McCain is impossible - and he>s
been tortured too. The Republicans have convinced themselves they>re
never wrong and businessmen never sin - that>s the Pelagian heresy, by
the way. Denial of original sin. These guys are Christians the same
way they>re capitalists.
[quote]
I have started taking Chlorella with a lot of good results. Chlorella
is not only an antiviral but also improves IL-10 synthesis and
rebalances the immune system. There>s even a report of it directly
suppressing allergic IgE responses to caesin in milk. I>m also
weighing
spirulina maxima, propolis, aspergillus, cillantro, mushroom extracts
and ecklonia cava. Clearly, I won>t try all of them.
Maybe I should give Chlorella a try but I>m almost allergic to
anything. I had total IgE`s of 8000 on a regular basis. Intestinal IgA
is nearly non existent anymore and pancreatic output is low as well.
NKs are down, RNase is up as is Elastase. My doctor says the virus
attacks the intestine and by that causes all the trouble you see in so
many people with CFS.
I wonder why you are doing so good mentally. I noticed a huge decline
in mental abbilities when everything started 5 years ago. There could
be lots of reasons, one being this:
"Dr Hiro Kuratsune from Japan gave a summary of what is known about
brain function in ME/CFS. It has been known for over a decade that
frontal and temporal lobe blood flow is reduced in ME/CFS, and that
exercise exacerbates this reduced blood flow for up to 72 hours. The
new evidence is that elevated elastase and RNase-L levels correlate
with reduced blood flow. It is known that the MRI is abnormal in the
majority of people with ME/CFS due to numerous T2 weighted
hypertintense foci, with evidence of demyelination."
http://www.meactionuk.org.uk/Facts from Florida.htm
[/quote]
I have the opposite reaction to exercise. I feel better afterwards.
Then again, I worked out 2-4 hours a day hard in college. That
conditioning might have spared me.
It>s possible I never had pure chronic fatigue - or it>s possible I
found ways to compensate for various declines in function. I don>t
know. I>m scared to get an MRI (again). The last MRI I had was a
disaster. I had to live with several partially herniated discs in my
neck because my neurologist - the fucker - couldn>t be bothered to walk
down to radiology and compare the notes from my pinprick exam to my
"average" abnormalities on the film that the radiologist assured him
couldn>t be causing the pain. At every place I had pain, I had an
"abnormality" that was in the realm of average (but, hell, people can
walk around with herniated discs and still be asymptomatic, so why look
for them in the first place?). When you>ve got mercury poisoning and
the shingles, those anatomical defects count for a lot. I had to yank
the films and take them to my dentist to get them read properly and even
then I didn>t get any real relief until I went to a physical therapist
for a year.
I didn>t just 'get' this way. People took my money to make me better
and instead they made me worse. The mercury, for instance, came out of
a cracked filling. Why does the industry put these fillings into people
who already have autoimmune problems and severe bruxism? Because nobody
kicks the shit out of them when they do. So where>s the incentive to
stop?
By the way, ever noticed what lidocaine does to HHV replication? The
lidocaine shots to my trigeminal nerve for my TMJ make a lot more sense
now...
Let me give you a few things to try. Keep in mind that carnitines may
increase your problems with viruses.
Acetyl-l-carnitine (which could raise your risk for brain and other
cancers and hair loss - p75 agonist, I>m afraid), could address the
fatigue. Mitocarnitine and the other carnitines wouldn>t agonize p75
but also wouldn>t affect ASIC3, which is involved in fatigue. A shot of
testosterone would help ASIC3 but it>s probably doing it via p75 and
carnitine transport anyway... (A PPARalpha agonist would help with
uptake... but again, increasing histone acetylation with butyrate might
help the virus which is probably why you>re in this catch-22 in the
first place).
Intestinal helminths. Great for autoantibodies and allergies.
Www.ovamed.com. Not perfect for me, but definitely an improvement.
Low-dose naltrexone.
Molybdenum (needed for metallothionein; would be bad for MT-expressing
tumors).
Vitamin D3
DHEA/testosterone/estrogen/progesterone
Intermittent fasting (autophagy)
B. fragilis/chlorella (for the IL-10)
Basically, I>m trying to fix defects in a chain of pathways that start
with butyrate/carnitine absorption in your gut: OCTN2->butyrate->mu
opioid/cannabinoids/metallothionein/cathelicidin/B-cell proliferation.
I>ve posted about all the branches before.
Have you ever been tested for heavy metals? |
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Kofi Guest
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Posted: Fri Oct 03, 2008 1:44 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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In article <48e4fa0b$0$504$ec3e2dad@news.usenetmonster.com>, katy
<katysails@netscape.com> wrote:
[quote]I was just diagnosed with celiac disease at the age of 56 after a bad
case of shingles. After a endoscopy>s, endoscopy and blood work for
every parasitical condition in the world, they did the celiac blood test
and then cross referenced to the results of the endoscopy and
colonoscopy. Said the results were at the high end of the table and that
the celiac disease caused microscopic colitis. I took the herpes
medication but it had no effect on the shingles, diarrhea, or anything
else that I could tell. Neither my gastroenterologist or the internist
made any correlation between the celiac disease and the shingles, so I
am going to bring that to their attention. Turns out that over the years
I have been misdiagnosed with various other food allergies and
conditions when all along I had celiac disease. At least now I know
[/quote]
"Welcome to the party, pal."
Say... Bruce Willis vs. American medicine? I think American medicine
would kick his ass every time. He might be able to take on the Death
Star, but not Joe Dentist, DDS. (Too many radioactive isotopes?)
Seriously, look for metals poisoning. It>s a factor in reawakened
varicella zoster infections and try Chlorella for starters. If you>ve
got metals poisoning, it will really make treating the virus difficult.
I thought at the time I was in the most pain, "Wow. This has got to be
as bad as the shingles at least." It felt like every bone in my body
was constantly being broken. I was even in pain when I was asleep,
which I didn>t know was possible. I>d read what mothers had said about
childbirth and the shingles and how they described it and I thought what
I had was in the same order. Seven years later my test results are in
and I finally know.
What did you do for the pain? Do you still have it? I>ve gotten good
relief from magnesium, methyl-B12, low-dose naltrexone and - you might
find this hard to believe - green tea extract topically applied in a 50%
distilled water/50% DMSO mixture. Turns out it>s a PPARalpha agonist,
which helps with pain and carnitine uptake. It>s also an antioxidant
and it helps inhibit viral replication. Also trips HIF-1a which I wrote
about recently. Anyway, as long as the skin is clean and the
ingredients pure, there>s little downside risk in it (as long as you
don>t mind waking up looking like Kermit with green sheets and pillows).
Famous last words, of course...
You might have these food allergies, you know. Just because you>re
making antibodies to gliaden, you>re not off the hook for antibodies to
other foods. In fact, the Celiac may have given you other problems like
those seen in IBD. To weed this out, you>ll need to pursue an allergy
elimination diet. Did you get a full viral panel? Is varicella all
you>ve got? Did they give you Valcyte or some sort of immunoglobulin
product or a vaccine for the shingles infection?
As long as you have that infection, you>ll want to avoid leukotriene
blockers. A lot of allergy medicines block LTB4, which is vital for
fighting the virus [PMID 17931111]. You should probably pick through
everything you take and see how it might affect the virus or even your
Celiac. There are so many ingredients in pills that cause problems for
Celiacs. |
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katy Guest
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Posted: Fri Oct 03, 2008 2:33 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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Kofi wrote:
[quote]In article <48e4fa0b$0$504$ec3e2dad@news.usenetmonster.com>, katy
katysails@netscape.com> wrote:
I was just diagnosed with celiac disease at the age of 56 after a bad
case of shingles. After a endoscopy>s, endoscopy and blood work for
every parasitical condition in the world, they did the celiac blood test
and then cross referenced to the results of the endoscopy and
colonoscopy. Said the results were at the high end of the table and that
the celiac disease caused microscopic colitis. I took the herpes
medication but it had no effect on the shingles, diarrhea, or anything
else that I could tell. Neither my gastroenterologist or the internist
made any correlation between the celiac disease and the shingles, so I
am going to bring that to their attention. Turns out that over the years
I have been misdiagnosed with various other food allergies and
conditions when all along I had celiac disease. At least now I know
"Welcome to the party, pal."
Say... Bruce Willis vs. American medicine? I think American medicine
would kick his ass every time. He might be able to take on the Death
Star, but not Joe Dentist, DDS. (Too many radioactive isotopes?)
Seriously, look for metals poisoning. It>s a factor in reawakened
varicella zoster infections and try Chlorella for starters. If you>ve
got metals poisoning, it will really make treating the virus difficult.
[/quote]
The shingles, thank goodness, have gone by the wayside...since I was
raised in an area 2 miles from a foundry and 8 miles from River Rouge,
MI, metal poisoning would not surprise me...
[quote]
What did you do for the pain?
[/quote]
Took diphenhydramine and Tramadol and mostly zonked myself out...I
should also mention I have a high pain threshold..have ahd 2 bone
grafts, one from an accident and another from a cancerous legion
(chondrosarcoma) so once you>ve had bone surgery, pain becomes a
relative thing...
Do you still have it?
I still have th scars on my abdomen...I had huge intense itching and it
baded the whole right side of my trunk and down into my groin...
I>ve gotten good
[quote]relief from magnesium, methyl-B12, low-dose naltrexone and - you might
find this hard to believe - green tea extract topically applied in a 50%
distilled water/50% DMSO mixture.
[/quote]
I did use a green tea moisturizer and got relief from it...
Turns out it>s a PPARalpha agonist,
[quote]which helps with pain and carnitine uptake. It>s also an antioxidant
and it helps inhibit viral replication. Also trips HIF-1a which I wrote
about recently. Anyway, as long as the skin is clean and the
ingredients pure, there>s little downside risk in it (as long as you
don>t mind waking up looking like Kermit with green sheets and pillows).
Famous last words, of course...
[/quote]
Doctor told me I could also use capseisin..that it aggravates the
shingles...I was loathe to do that though becasue I wear contacts and
that stuff is hard to get off your hands, even scrubbing ruthlessly
(past experience speaking...not pleeasant...)
[quote]
You might have these food allergies, you know. Just because you>re
making antibodies to gliaden, you>re not off the hook for antibodies to
other foods. In fact, the Celiac may have given you other problems like
those seen in IBD. To weed this out, you>ll need to pursue an allergy
elimination diet
[/quote]
I>ve had two in the past..they were contradictory..I am lactose
intolerant for sure and do have allergies for walnuts and pecans
(anaphylactic reactions) I am also allergic to both penicillin and
sulpha...one test said I was allergic to peaches, strawberries and
tomatoes, but they never give me any grief...allergist said I was
probably having an intolerant reaction because my immune system was
already overstimulated and sometimes you>ll get false results...the
second test did not show these things..
.. Did you get a full viral panel?
I don>t know...I went into this whole thing uninformed on what I should
be asking...
Is varicella all
[quote]you>ve got?
[/quote]
Don>t know..
Did they give you Valcyte or some sort of immunoglobulin
[quote]product or a vaccine for the shingles infection?
[/quote]
They gave me Valtrex for the shingles. I take diphenhydramine for
allergic reactions and Zyrtec daily...I am also now taking Asacol (sp)
I cannot take oral steroids, ehich was one suggestion...I do the steroid
freaky thing on them and get very paranoid...
[quote]
As long as you have that infection, you>ll want to avoid leukotriene
blockers.
[/quote]
I don>t take Singular, so should be fine...
A lot of allergy medicines block LTB4, which is vital for
[quote]fighting the virus [PMID 17931111]. You should probably pick through
everything you take and see how it might affect the virus or even your
Celiac. There are so many ingredients in pills that cause problems for
Celiacs.
[/quote]
The pharmacist at our local pharmacy has been very helpful and even
supplied a list that Walgreen>s has for OTC gluten free drugs...said if
something comes up they could always formulate themspeves... |
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rs1000b@yahoo.com Guest
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Posted: Fri Oct 03, 2008 3:26 am Post subject: Re: Aluminium induced electrophysiological, biochemical and |
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On Oct 1, 9:42 am, "D. C. Sessions" <d...@lumbercartel.com> wrote:
[quote]50 mg/kg per day?
That would be over a pound of ingested aluminum daily for a 70 kg
human. How many Maalox does that take?
(I daresay that your cookware wouldn>t last long at that rate either!)
[/quote]
This is from the introduction in the full text:
"Al is routinely used as a water treatment reagent and is often added
in the processing of food and
pharmaceutical products (antacids). Therefore, our daily intake of
aluminium ranges from 10-20
mg/kg via digestive and respiratory tract (Edwardson et al., 1992)."
Edwardson JA, Candy JM, Ince PG, McArthur FK, Morris CM, Oakley AE,
Taylor GA, Bjertness E.
"Aluminium accumulation, beta-amyloid deposition and neurofibrillary
changes in the central nervous system."
Ciba Foundation
Symposium. 1992;169: 165–79. |
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Taka Guest
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Posted: Fri Oct 03, 2008 3:34 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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On Oct 3, 8:23 am, Kofi <k...@anon.un> wrote:
[quote]You really, really need to avoid tomatoes if you>ve got any inflammation
at all. There>s a diet for M.S. patients that should help anybody with
nerve damage. Nightshades are very inflammatory.
[/quote]
Could you explain please how nightshades can be inflammatory? Any
references or molecular clues?
Taka
[quote]So are sweet fruits
because of the glucose they release. It somehow stimulates B- and
T-cell production. Not good for autoimmune problems.[/quote] |
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Kofi Guest
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Posted: Fri Oct 03, 2008 4:23 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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[quote]I>ve had two in the past..they were contradictory..I am lactose
intolerant for sure and do have allergies for walnuts and pecans
(anaphylactic reactions) I am also allergic to both penicillin and
sulpha...one test said I was allergic to peaches, strawberries and
tomatoes, but they never give me any grief...allergist said I was
probably having an intolerant reaction because my immune system was
already overstimulated and sometimes you>ll get false results...the
second test did not show these things..
[/quote]
You really need to use the elimination diet and just see if you feel
better. If adding strawberries back to your base diet doesn>t result in
any problems after a week or two, you probably don>t have problems.
You really, really need to avoid tomatoes if you>ve got any inflammation
at all. There>s a diet for M.S. patients that should help anybody with
nerve damage. Nightshades are very inflammatory. So are sweet fruits
because of the glucose they release. It somehow stimulates B- and
T-cell production. Not good for autoimmune problems.
[quote]
. Did you get a full viral panel?
I don>t know...I went into this whole thing uninformed on what I should
be asking...
[/quote]
You might want to test for antibodies to HHV1-6. I had a fairly
inexpensive kit that did it.
[quote]
Is varicella all
you>ve got?
Don>t know..
Did they give you Valcyte or some sort of immunoglobulin
product or a vaccine for the shingles infection?
They gave me Valtrex for the shingles. I take diphenhydramine for
allergic reactions and Zyrtec daily...I am also now taking Asacol (sp)
I cannot take oral steroids, ehich was one suggestion...I do the steroid
freaky thing on them and get very paranoid...
[/quote]
Valtrex is a prodrug, which means it has to be converted into aciclovir
in the body by the liver. I>m wondering if your doctors have tested to
see if you can convert it properly. |
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Kofi Guest
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Posted: Fri Oct 03, 2008 4:24 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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[quote]
What did you do for the pain?
Took diphenhydramine and Tramadol and mostly zonked myself out...I
should also mention I have a high pain threshold..
[/quote]
Are you a redhead? Have a redheaded parent? |
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katy Guest
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Posted: Fri Oct 03, 2008 5:26 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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Kofi wrote:
[quote]What did you do for the pain?
Took diphenhydramine and Tramadol and mostly zonked myself out...I
should also mention I have a high pain threshold..
Are you a redhead? Have a redheaded parent?
[/quote]
I>m a brunette with heavy auburn highlights...mother brunette, father
black hair....I am olive skintone.... |
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Taka Guest
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Posted: Fri Oct 03, 2008 3:50 pm Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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On Oct 3, 5:27 pm, jackson.alo...@googlemail.com wrote:
[quote]On 2 Okt., 22:44, Kofi <k...@anon.un> wrote:
In article <48e4fa0b$0$504$ec3e2...@news.usenetmonster.com>, katy
As long as you have that infection, you>ll want to avoid leukotriene
blockers. A lot of allergy medicines block LTB4, which is vital for
fighting the virus [PMID 17931111]. You should probably pick through
everything you take and see how it might affect the virus or even your
Celiac. There are so many ingredients in pills that cause problems for
Celiacs.
Would it be possible to take some LTB4 in order to treat a CMV
infection? Is this also valid for HHV6 or 7? That>s really good to
know, I>m about to throw away the Singulair (I just took it once a
week or less) and won>t buy it again.
[/quote]
This is even more ridiculous than taking Omega-3 to counteract Omega-6
overload ... If you want to "supplement" LTB4 to get rid of viral
infections you have my condolences, this is the most dangerous
signaling molecule around. Kofi, have you ever tried to lower the
PUFAs in your body? Maybe that would take care of your viral
"infections" and you may recover like Monty recovered from his
"wasting disease".
Taka |
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rs1000b@yahoo.com Guest
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Posted: Sat Oct 04, 2008 5:29 am Post subject: Re: Aluminium induced electrophysiological, biochemical and |
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On Oct 1, 9:42 am, "D. C. Sessions" <d...@lumbercartel.com> wrote:
[quote]rs10...@yahoo.com wrote:
Aluminium (Al) is the most abundant metal, known for its neurotoxicity
in humans. It gains easy access to the central nervous system under
normal physiological conditions and accumulates in different brain
regions. It has been reported to be involved in the etiology of
several neurodegenerative diseases. In this study, we have
investigated the effects of long-term intake of aluminium chloride
(AlCl(3)) on the electrophysiological, behavioral, biochemical and
histochemical functions of hippocampus. Wistar rats were fed with
AlCl(3) at a dose of 50mg/(kgday) for 6 months in the drinking water.
Effect of long-term intake of Al was studied on the neuronal and
electrical activity of hippocampal CA1 and CA3 regions in brain of
young and old rats. Morris water maze and open field tests were
performed to investigate the cognitive and anxiety status of aging
rats intoxicated with aluminium. Our studies indicate that aluminium
intake results in increased multiple unit activity and adversely
affect the spatial learning and memory abilities of both young and old
rats. Aluminium intake also inflicts oxidative stress related damages
to lipids, membrane associated proteins (Na-K ATPase and PKC) and
endogenous antioxidant enzyme activity (SOD, GPx and GST). The
compromised antioxidant system might be playing a crucial role in the
observed Al induced alterations. We have observed that magnitude of
AlCl(3) induced alteration was considerably higher in younger group of
rats compared to older group. In conclusion, the results of the
present study implicates that aluminium treatment exerts its
neurotoxic effects by altering overall physiology of brain and induced
changes were strongly correlated with each other.
50 mg/kg per day?
That would be over a pound of ingestedaluminumdaily for a 70 kg
human.
[/quote]
I suggest you re-check your math. :-) |
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katy Guest
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Posted: Sat Oct 04, 2008 5:29 am Post subject: Re: redheads, celiac and opiates |
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Kofi wrote:
[quote]In article <48e58be7$0$554$ec3e2dad@news.usenetmonster.com>,
katy <katysails@netscape.com> wrote:
Kofi wrote:
What did you do for the pain?
Took diphenhydramine and Tramadol and mostly zonked myself out...I
should also mention I have a high pain threshold..
Are you a redhead? Have a redheaded parent?
I>m a brunette with heavy auburn highlights...mother brunette, father
black hair....I am olive skintone....
The mutation for red hair is a non-functional MC-1 mutation. It>s not
necessarily dominant. It prevents alpha-MSH from docking to its
receptor (MC-1) and leaves opiates floating around longer in the blood.
This results in greater analgesia when a burst of pain releases
endogenous endorphins. Redheaded women have the highests tolerance for
pain, followed by redheaded men, followed by the rest of men, followed
by the rest of women. Since caesin and gluten are also processed into
opiates when they>re digested, I have a theory I wrote about a few years
back that people who have this redheaded gene (and they wouldn>t
necessarily be pure redheads) would be more vulnerable to autoimmune
problems revolving around gluten, caesin and other nutritional opioids
(like rice, red meat and maybe spinach too) because the antigens would
float around in these individuals longer before they broke down. When
you mentioned high tolerance to pain and a gluten problem, I played the
probabilities and took a guess.
[/quote]
That>s interesting...I just always thought I was a syoic persoanlity
type.... |
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Rufus Guest
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Posted: Sat Oct 04, 2008 5:29 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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Kofi wrote:
[quote]In article
ae118358-1778-4400-aa49-1d1c2e0d60ad@17g2000hsk.googlegroups.com>,
Taka <taka0038@gmail.com> wrote:
On Oct 3, 8:23 am, Kofi <k...@anon.un> wrote:
You really, really need to avoid tomatoes if you>ve got any inflammation
at all. There>s a diet for M.S. patients that should help anybody with
nerve damage. Nightshades are very inflammatory.
Could you explain please how nightshades can be inflammatory? Any
references or molecular clues?
No. I just took it as a pointer from an M.S. diet and it worked for me.
I can>t remember why off the top of my head and I>ve got no notes on it.
[/quote]
This is kind of interesting...informationally...
http://www.whfoods.com/genpage.php?tname=george&dbid=62
....but I>d recommend just Googling "nightshades". I suspect the issue
for people with IBD is the alkaline content of nightshades, however, I
recall being warned off tomatoes by the hospital dietitian because they
are highly acidic...at least that was what I surmised at the time...I
suppose she could have meant alkaline reactive; she just told me "you>ll
have to avoid tomatoes from now on" when I was released. Ever seen what
tomato sauce does to an aluminum pot if you leave it?..I avoid tomatoes
religiously...mostly...
I made the mistake of eating a bit too much pizza at a retirement party
last week...I>m still paying for it, discomfort-wise.
--
- Rufus |
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Kofi Guest
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Posted: Sat Oct 04, 2008 5:29 am Post subject: Re: Herpesviruses secrete phony IL-10; might cause autoimmun |
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In article
<6152f1b2-b811-48a1-9c50-75145bd4bcfa@l64g2000hse.googlegroups.com>,
Taka <taka0038@gmail.com> wrote:
[quote]On Oct 3, 5:27 pm, jackson.alo...@googlemail.com wrote:
On 2 Okt., 22:44, Kofi <k...@anon.un> wrote:
In article <48e4fa0b$0$504$ec3e2...@news.usenetmonster.com>, katy
As long as you have that infection, you>ll want to avoid leukotriene
blockers. A lot of allergy medicines block LTB4, which is vital for
fighting the virus [PMID 17931111]. You should probably pick through
everything you take and see how it might affect the virus or even your
Celiac. There are so many ingredients in pills that cause problems for
Celiacs.
Would it be possible to take some LTB4 in order to treat a CMV
infection? Is this also valid for HHV6 or 7? That>s really good to
know, I>m about to throw away the Singulair (I just took it once a
week or less) and won>t buy it again.
This is even more ridiculous than taking Omega-3 to counteract Omega-6
overload ... If you want to "supplement" LTB4 to get rid of viral
infections you have my condolences, this is the most dangerous
signaling molecule around. Kofi, have you ever tried to lower the
PUFAs in your body? Maybe that would take care of your viral
"infections" and you may recover like Monty recovered from his
"wasting disease".
Taka
[/quote]
It>s not ridiculous. It>s a valid theory that deserves testing and,
yes, there could by collateral systemic inflammatory damage just as
there is with boosting IDO.
Interestingly, pollen-associated lipid mediators contain LTB4 ligands
[PMID 15208598]. Notice how propolis in honey has antiviral properties.
Maybe there>s a connection here.
You want to avoid theophylline too [PMID 16086060], by the way. If this
theory is right, lyprinol is also counterindicated [PMID 11094642] and
also vitamin E>s [PMID 17272491].
Interestingly, LTB4 binds to PPARalpha and triggers transcription of its
downstream oxidation elements
<http://joe.endocrinology-journals.org/cgi/reprint/169/3/453> and
PPARalpha agonists triggers carnitine uptake which starts off the
butyrate metabolism in the gut that is so deficient in people with
colitis/IBD. Connection? CMV would want to pipe down LTB4...
FYI, oleic acid and fish oils are fatty acid synthase inhibitors,
meaning they might generically inhibit viral production by preventing
viruses from making their coats. Drinking olive oil might be quite
helpful for CMV infections, though of course that claim remains to be
measured with real life data.
Since cathelicidin mediates the antiviral response of LTB4, one would
expect cathelicidin agonists like vitamin D3 and butyrate to also
stimulate antiviral action - which further complicates the butyrate
picture given how it also wakes up some or all herpesviruses. HIF-1a
also stimulates cathelicidin in some circumstances, so it could be part
of an antiviral response too. |
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